Recomendaciones GESIDA/SEFH/PNS para mejorar la adherencia al tratamiento antirretroviral en el año 2004

Translated title of the contribution: Recommendations from GESIDA/SEFH/PNS to improve adherence to antiviral treatment (2004)

Hernando Knobel, Ismael Escobar*, Rosa Polo, Luis Ortega, Ma Teresa Martín-Conde, José Luis Casado, Carlos Codina, Josefina Fernández, Ma José Galindo, Olatz Ibarra, Monserrat Llinas, Celia Miralles, Melcior Riera, Carmina R. Fumaz, Aurea Segador, Ferran Segura, Lourdes Chamorro

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)


Since the early days of antiretroviral therapy, adherence has emerged as the milestone of success; in fact, it is the most potent predictor of effectiveness. The main factors related to adherence include the complexity of the therapeutic regimen, adverse effects, psychological problems, alcoholism and active addiction to drugs, lack of social and family support and the patient's beliefs and attitudes about the treatment. Adherence monitoring should be part of the HIV patient's regular care, and should be done with feasible, easily applied methods adapted to the different clinical settings. The minimally acceptable measures should include use of a validated questionnaire, together with data from the Pharmacy Department's drug dispensation registry. All patients that begin HAART or undergo a change of treatment should participate in a treatment education program imparted by health professionals with knowledge and experience in the management of patients with HIV infection. The health team (doctors, pharmacists and nursing professionals) should offer maximum availability to solve the doubts and problems that may occur during treatment. When sub-optimal adherence is detected, intervention strategies based on psychological therapy, educational efforts and personal advice should be attempted, in order to adapt the treatment scheme to the patient's habits and provide solutions to the problem of non-compliance. In certain situations, co-morbid conditions will also require attention. Treatment adherence, being a multidimensional problem, needs a multidisciplinary team approach. The choice of therapy, only one aspect of the multidimensional problem of adherence, must be a careful and individualized decision; however, simpler regimens with regard to the number of pills and daily dose are desirable.

Translated title of the contributionRecommendations from GESIDA/SEFH/PNS to improve adherence to antiviral treatment (2004)
Original languageSpanish
Pages (from-to)221-231
Number of pages11
JournalEnfermedades Infecciosas y Microbiologia Clinica
Issue number4
Publication statusPublished - Apr 2005


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