TY - JOUR
T1 - Recent advances in the synthesis of azaphenalene alkaloids: First enantioselective approaches
AU - Alujas-Burgos, Sílvia
AU - Bayón, Pau
AU - Figueredo, Marta
PY - 2018/1/1
Y1 - 2018/1/1
N2 - © 2018 The Royal Society of Chemistry. Azaphenalene alkaloids are biosynthesised and segregated by diverse insects of the Coccinellidae family (ladybirds) and are believed to play an important role in the defensive mechanism against their natural predators. The particular unique framework of these alkaloids, along with their potential in the field of biological pest control, has led to several research groups developing synthetic sequences to prepare these compounds. The main purpose of the present review is to provide an update of the more recent synthetic progress towards these alkaloids, including the pioneering enantioselective approaches to chiral congeners.
AB - © 2018 The Royal Society of Chemistry. Azaphenalene alkaloids are biosynthesised and segregated by diverse insects of the Coccinellidae family (ladybirds) and are believed to play an important role in the defensive mechanism against their natural predators. The particular unique framework of these alkaloids, along with their potential in the field of biological pest control, has led to several research groups developing synthetic sequences to prepare these compounds. The main purpose of the present review is to provide an update of the more recent synthetic progress towards these alkaloids, including the pioneering enantioselective approaches to chiral congeners.
U2 - https://doi.org/10.1039/c8ob01443d
DO - https://doi.org/10.1039/c8ob01443d
M3 - Review article
C2 - 30168549
VL - 16
SP - 6840
EP - 6851
JO - Organic and Biomolecular Chemistry
JF - Organic and Biomolecular Chemistry
SN - 1477-0520
IS - 37
ER -