Recent advances in the epidemiology, diagnosis and control of diseases caused by porcine circovirus type 2

Llorenç Grau-Roma, Lorenzo Fraile, Joaquim Segalés

Research output: Contribution to journalReview articleResearchpeer-review

106 Citations (Scopus)

Abstract

Post-weaning multisystemic wasting syndrome (PMWS) emerged as a significant disease affecting pig production in the 1990s although the causal agent, porcine circovirus type 2 (PCV2), and the disease itself, had existed in swine for many years prior to this. The important multifactorial 'triggers' of PMWS include the immune and infection status of the sow, the timing of PCV2 infection, variations in the virulence of PCV2, co-infections, immune modulation as well as host genetics and management factors. In terms of diagnosis, histopathological examination and the detection of PCV2 within lymphoid tissue remains the 'gold standard' as quantitative PCR techniques are currently not specific or sensitive enough. The recent commercial availability of PCV2 vaccines provides an excellent tool for reducing the impact of PMWS and other porcine circovirus-related diseases. This review assesses recent advances in the epidemiology, diagnosis and control of PMWS. © 2010 Elsevier Ltd.
Original languageEnglish
Pages (from-to)23-32
JournalVeterinary Journal
Volume187
Issue number1
DOIs
Publication statusPublished - 1 Jan 2011

Keywords

  • Control
  • Diagnosis
  • Epidemiology
  • Porcine circovirus type 2 (PCV2)
  • Post-weaning multisystemic wasting syndrome (PMWS)

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