We report the case of an exhuberant ulcerative angiomatoid nasal lesion in a cocaine abuser. The lesion was made up of polimorphous endothelial cells with occasional mitoses, arranged in a lobular pattern with infiltrative- looking areas. There were extensive areas of thrombosis with focal recanalization. Intravascular proliferation was not observed. The clinical, radiological, and histological features suggested hemangiosarcoma as the main differential diagnosis, but the lobular architecture of the lesion and the widespread thrombosis favoured the diagnosis of a benign reactive process. (C) 2000 W.B. Saunders Company.
- Angioendotheliomatosis proliferans
- Cocaine abuser
- Nasal mucosa
- Nasal tumor
- Nasal ulcer