Reaction of β-cyclodextrin with N-2,3-epoxypropylphthalimide. Preparation, characterisation and study of a new substituted cycloheptaamylose. Effects on the water solubility of drugs

Raquel Delgado, Albert Virgil, J. M. Garcia-Anton, A. Parente

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Abstract

The reaction of β-cyclodextrin with N-2,3-epoxypropylphthalimide yielded a set of new amorphous host compounds with high solubility which was transmitted to the corresponding host-guest complexes. The structure was determined by comparing the 1H-and 13C-NMR spectra with those of the parent compound, the degree of substitution by integration of the corresponding NMR signals, and C, H, and N elemental analysis.
Original languageEnglish
Pages (from-to)205-212
JournalJournal of Inclusion Phenomena and Molecular Recognition in Chemistry
Volume28
DOIs
Publication statusPublished - 1 Jan 1997

Keywords

  • Amorphous
  • Epoxides
  • β-Cyclodextrin (β-CD)

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