@article{a8a0cd4413444dd2a0461a1777c694d7,
title = "Rates of cardiovascular disease following smoking cessation in patients with HIV infection: Results from the D:A:D study",
abstract = "Objectives: The aim of the study was to estimate the rates of cardiovascular disease (CVD) events after stopping smoking in patients with HIV infection. Methods: Patients who reported smoking status and no previous CVD prior to enrolment in the Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) study were included in this study. Smoking status is collected at each visit as current smoker (yes/no) and ever smoker (yes/no). Time since stopping smoking was calculated for persons who had reported current smoking during follow-up and no current smoking subsequently. Endpoints were: myocardial infarction (MI); coronary heart disease (CHD: MI plus invasive coronary artery procedure or death from other CHD); CVD (CHD plus carotid artery endarterectomy or stroke); and all-cause mortality. Event rates were calculated for never, previous and current smokers, and smokers who stopped during follow-up. Incidence rate ratios (IRRs) were determined using Poisson regression adjusted for age, sex, cohort, calendar year, family history of CVD, diabetes, lipids, blood pressure and antiretroviral treatment. Results: A total of 27136 patients had smoking status reported, with totals of 432, 600, 746 and 1902 MI, CHD, CVD and mortality events, respectively. The adjusted IRR of CVD in patients who stopped smoking during follow-up decreased from 2.32 within the first year of stopping to 1.49 after >3 years compared with those who never smoked. Similar trends were observed for the MI and CHD endpoints. Reductions in risk were less pronounced for all-cause mortality. Conclusion: The risk of CVD events in HIV-positive patients decreased with increasing time since stopping smoking. Smoking cessation efforts should be a priority in the management of HIV-positive patients. {\textcopyright} 2011 British HIV Association.",
keywords = "Cardiovascular disease, Cohort study, HIV infection, Myocardial infarction, Smoking cessation, antihypertensive agent, antilipemic agent, antiretrovirus agent, high density lipoprotein cholesterol, proteinase inhibitor, triacylglycerol, angioplasty, antihypertensive therapy, antiviral therapy, article, cardiovascular disease, carotid endarterectomy, cholesterol blood level, coronary artery bypass graft, diabetes mellitus, diastolic blood pressure, family history, female, follow up, gender, heart infarction, human, Human immunodeficiency virus infected patient, Human immunodeficiency virus infection, ischemic heart disease, major clinical study, male, priority journal, prospective study, smoking, smoking cessation, systolic blood pressure, triacylglycerol blood level, virus load, Adult, Argentina, Cardiovascular Diseases, CD4 Lymphocyte Count, Cohort Studies, Europe, Female, HIV Infections, Humans, Incidence, Male, Middle Aged, Prospective Studies, Risk Factors, Smoking, Smoking Cessation, United States",
author = "K. Petoumenos and S. Worm and P. Reiss and {de Wit}, S. and {d'Arminio Monforte}, A. and C. Sabin and N. Friis-M{\o}ller and R. Weber and P. Mercie and C. Pradier and W. El-Sadr and O. Kirk and J. Lundgren and M. Law and Ferran Torres",
note = "Cited By :139 Export Date: 17 February 2022 CODEN: HMIEA Correspondence Address: Petoumenos, K.; AHOD, 45 Beach Street, Sydney, NSW 2034, Australia; email: kpetoumenos@nchecr.unsw.edu.au Chemicals/CAS: proteinase inhibitor, 37205-61-1 Funding details: National Institute of Allergy and Infectious Diseases, NIAID, U01AI042170, U01AI046362, U01AI069907 References: Grierson, J., Thorpe, R., Saunders, M., Pitts, M., (2004) HIV Futures4: State of the [Positive] Nation, Monograph Series Number 48, , The Australian Research Centre in Sex, Health and Society, Latrobe University, Melbourne, Australia; Benard, A., Bonnet, F., Tessier, J.F., Tobacco addiction and HIV infection (2007) toward the implementation of cessation programs. ANRS CO3 Aquitaine Cohort, 21, pp. 458-468. , AIDS Patient Care STDS; Duval, X., Baron, G., Garelik, D., Living with HIV, antiretroviral treatment experience and tobacco smoking (2008) results from a multisite cross-sectional study, 13, pp. 389-397. , Antivir Ther; Tesoriero, J.M., Gieryic, S.M., Carrascal, A., Lavigne, H.E., Smoking among HIV positive New Yorkers: prevalence, frequency, and opportunities for cessation (2010) AIDS Behav, 14, pp. 824-835; Mamary, E.M., Bahrs, D., Martinez, S., Cigarette smoking and the desire to quit among individuals living with HIV (2002) AIDS Patient Care STDS, 16, pp. 39-42; Crothers, K., Goulet, J.L., Rodriguez-Barradas, M.C., Decreased awareness of current smoking among health care providers of HIV-positive compared to HIV-negative veterans (2007) J Gen Intern Med, 22, pp. 749-754; Friis-Moller, N., Weber, R., Reiss, P., Cardiovascular disease risk factors in HIV patients-association with antiretroviral therapy. Results from the DAD study (2003) AIDS, 17, pp. 1179-1193; Crothers, K., Griffith, T.A., McGinnis, K.A., The impact of cigarette smoking on mortality, quality of life, and comorbid illness among HIV-positive veterans (2005) J Gen Intern Med, 20, pp. 1142-1145; Clifford, G.M., Polesel, J., Rickenbach, M., Cancer risk in the Swiss HIV Cohort Study: associations with immunodeficiency, smoking, and highly active antiretroviral therapy (2005) J Natl Cancer Inst, 97, pp. 425-432; Burns, D.N., Hillman, D., Neaton, J.D., Cigarette smoking, bacterial pneumonia, and other clinical outcomes in HIV-1 infection. Terry Beirn Community Programs for Clinical Research on AIDS (1996) J Acquir Immune Defic Syndr Hum Retrovirol, 13, pp. 374-383; Conley, L.J., Bush, T.J., Buchbinder, S.P., Penley, K.A., Judson, F.N., Holmberg, S.D., The association between cigarette smoking and selected HIV-related medical conditions (1996) AIDS, 10, pp. 1121-1126; Caiaffa, W.T., Vlahov, D., Graham, N.M., Drug smoking, Pneumocystis carinii pneumonia, and immunosuppression increase risk of bacterial pneumonia in human immunodeficiency virus-seropositive injection drug users (1994) Am J Respir Crit Care Med, 150, pp. 1493-1498; Crothers, K., Butt, A.A., Gibert, C.L., Rodriguez-Barradas, M.C., Crystal, S., Justice, A.C., Increased COPD among HIV-positive compared to HIV-negative veterans (2006) Chest, 130, pp. 1326-1333; Kirk, G.D., Merlo, C., O'Driscoll, P., HIV infection is associated with an increased risk for lung cancer, independent of smoking (2007) Clin Infect Dis, 45, pp. 103-110; Bonnet, F., Lewden, C., May, T., Malignancy-related causes of death in human immunodeficiency virus-infected patients in the era of highly active antiretroviral therapy (2004) Cancer, 101, pp. 317-324; Mercie, P., Thiebaut, R., Lavignolle, V., Evaluation of cardiovascular risk factors in HIV-1 infected patients using carotid intima-media thickness measurement (2002) Ann Med, 34, pp. 55-63; Friis-Moller, N., Sabin, C.A., Weber, R., Combination antiretroviral therapy and the risk of myocardial infarction (2003) N Engl J Med, 349, pp. 1993-2003; Monforte, A., Abrams, D., Pradier, C., HIV-induced immunodeficiency and mortality from AIDS-defining and non-AIDS-defining malignancies (2008) AIDS, 22, pp. 2143-2153; Palella Jr, F.J., Baker, R.K., Moorman, A.C., Mortality in the highly active antiretroviral therapy era: changing causes of death and disease in the HIV outpatient study (2006) J Acquir Immune Defic Syndr, 43, pp. 27-34; Lewden, C., Salmon, D., Morlat, P., Causes of death among human immunodeficiency virus (HIV)-infected adults in the era of potent antiretroviral therapy: emerging role of hepatitis and cancers, persistent role of AIDS (2005) Int J Epidemiol, 34, pp. 121-130; Lloyd-Richardson, E.E., Stanton, C.A., Papandonatos, G.D., Motivation and patch treatment for HIV+smokers (2009) a randomized controlled trial, 104, pp. 1891-1900. , Addiction; Wolf, P.A., D'Agostino, R.B., Kannel, W.B., Bonita, R., Belanger, A.J., Cigarette smoking as a risk factor for stroke. The Framingham study (1988) JAMA, 259, pp. 1025-1029; Wannamethee, S.G., Shaper, A.G., Whincup, P.H., Walker, M., Smoking cessation and the risk of stroke in middle-aged men (1995) JAMA, 274, pp. 155-160; Tverdal, A., Thelle, D., Stensvold, I., Leren, P., Bjartveit, K., Mortality in relation to smoking history: 13 years' follow-up of 68,000 Norwegian men and women 35-49 years (1993) J Clin Epidemiol, 46, pp. 475-487; Rosenberg, L., Kaufman, D.W., Helmrich, S.P., Shapiro, S., The risk of myocardial infarction after quitting smoking in men under 55 years of age (1985) N Engl J Med, 313, pp. 1511-1514; Godtfredsen, N.S., Holst, C., Prescott, E., Vestbo, J., Osler, M., Smoking reduction, smoking cessation, and mortality (2002) Am J Epidemiol, 156, pp. 994-1001. , a 16-year follow-up of 19,732 men and women from The Copenhagen Centre for Prospective Population Studies; Doll, R., Peto, R., Boreham, J., Sutherland, I., Mortality in relation to smoking (2004) 50 years' observations on male British doctors, 328, p. 1519. , BMJ; Benard, A., Mercie, P., Alioum, A., (2010), 5, pp. e8896. , Bacterial Pneumonia among HIV-infected patients: decreased risk after tobacco smoking cessation. ANRS CO3 Aquitaine Cohort, 2000-2007. PLoS One; Friis-Moller, N.R.T., Reiss, P., Weber, R., Predicting the risk of cardiovascular disease in HIV-infected patients; The Data-collection on Adverse Effects of Anti-HIV Drugs (D:A:D) Study (2010) Eur J Cardiovasc Prev Rehabil, 17, pp. 491-501; Sabin, C.A., Worm, S.W., Weber, R., Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients enrolled in the D:A:D study (2008) a multi-cohort collaboration, 371, pp. 1417-1426. , Lancet; Worm, S.W., Sabin, C., Weber, R., Risk of myocardial infarction in patients with HIV infection exposed to specific individual antiretroviral drugs from the 3 major drug classes (2010) J Infect Dis, 201, pp. 318-330. , the data collection on adverse events of anti-HIV drugs (D:A:D) study",
year = "2011",
month = aug,
doi = "10.1111/j.1468-1293.2010.00901.x",
language = "English",
volume = "12",
pages = "412--421",
journal = "HIV Medicine",
issn = "1464-2662",
number = "7",
}