Qxpak: A versatile mixed model application for genetical genomics and QTL analyses

Research output: Contribution to journalArticleResearchpeer-review

111 Citations (Scopus)

Abstract

Motivation: Current methodology and software for quantitative trait loci (QTL) analyses do not use all available information and are inadequate to deal with the huge amount of QTL analyses to be needed in forecoming genetical genomics' studies. Results: We show that a mixed model statistical framework provides a very flexible tool for QTL modeling in a variety of populations, be it a cross between inbred lines, a within population study, or experiments involving a mixture of populations or crosses. The software allows multitrait and multiQTL analyses, inclusion of infinitesimal genetic value and a batch multitrait option suitable for genetical genomics studies. It also allows massive association studies between single nucleotide polymorphisms and the trait(s) of interest. © Oxford University Press 2004; all rights reserved.
Original languageEnglish
Pages (from-to)2792-2798
JournalBioinformatics
Volume20
Issue number16
DOIs
Publication statusPublished - 1 Nov 2004

Fingerprint Dive into the research topics of 'Qxpak: A versatile mixed model application for genetical genomics and QTL analyses'. Together they form a unique fingerprint.

Cite this