High-dose chemotherapy with autologous bone marrow or peripheral stem cell support is frequently used for the treatment of high-risk pediatric solid tumors. The gained experience with these treatments runs parallel with a considerable decrease on the procedure- related complications. These strategies have demonstrated its efectivity in the treatment of high-risk neuroblastoma as well as in refractory or relapsed germ cell tumors. There are also evidences showing that its use in high-risk Ewing's sarcoma, and in chemosensitive relapsed or metastatatic brain tumors, contributes to ameliorate the dismal prognosis of these patients.
|Translated title of the contribution||Intensive chemotherapy with stem cell support in non-hematological pediatric solid tumors: State of the art|
|Number of pages||6|
|Journal||Clinical and Translational Oncology|
|Publication status||Published - Jan 2001|