Prospective pilot study of cognitive impairment in palliative oncologic outpatients

Joan Deus I Yela, J. L. Villar-Fernández, M. Salas-Cortés, N. Antoñana-Michelena, E. Rodés-García, J. Pujol, T. Gutiérrez-Rosado, F. Villafaña-Tudela, M. Hernández-Bronchud

    Research output: Contribution to journalArticleResearchpeer-review

    Abstract

    Several studies suggest that cognitive impairment can often appear in advanced cancer patients. Its prevalence is very variable (8-90%) and there is very little prospective research with palliative outpatients. Objective: studying the prevalence of the cognitive impairment in palliative oncologic outpatients and specifying the most sensitive cognitive screening test. Method: Subjects: sixteen onchological palliative patients, 7 men and 9 women, with an average age of 73 years old (±12,9) and 3,8 school years (±3,3). The main diagnosis was the digestive neoplasia. During the cognitive examination, three of the patients were being treated with morphic. Material: a battery of cognitive tests was administered in an ambulatory way. This battery included the mini-exam cognitive of Lobo (MEC), the cognitive evaluation scale of Clifton (CAS), the quick assessment of cognitive function of Gil (ERFC) and the subtest of digit symbol from WAIS-III. Results: four patients was excluded, after neuropsychological assessment, because they showed a diffuse cortical cognitive failure, which suggested the possibility of the existence of dementia. CAS and ERFC showed, in the rest of the 12 patients, a light cognitive impairment in 4 and 9 of the subjects, respectively. By the use of MEC, only one case was detected. Conclusion: the majority of the palliative onchological outpatients have specific light cognitive deterioration. MEC seems to have less perceptibility than CAS and ERFC to detect that impairment. The slowness of mind activity and movements seem to be the most common cognitive failure in this group of outpatients. Finally, cognitive failure is not related to mortality risk. Copyright © 2005 ARÁN EDICIONES, S.L.
    Original languageEnglish
    Pages (from-to)6-11
    JournalMedicina Paliativa
    Volume12
    Issue number1
    Publication statusPublished - 1 Jan 2005

    Keywords

    • Advanced cancer
    • Cognitive failure
    • Cognitive impairment
    • Neuropsychological assessment
    • Palliative oncologic outpatients
    • Prospective research

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