Prognostic value of body mass index and waist circumference in patients with chronic heart failure (Spanish REDINSCOR registry)

Teresa Puig, Andreu Ferrero-Gregori, Eulalia Roig, Rafael Vazquez, Jose R. Gonzalez-Juanatey, Domingo Pascual-Figal, Juan Delgado, Luis Alonso-Pulpon, Xavier Borras, Ana Mendez, Juan Cinca

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16 Citations (Scopus)

Abstract

Objectives: To analyze the association between higher body mass index and waist circumference, and the prognostic values of both indicators in total and cardiac mortality in patients with chronic heart failure. Methods: The study included 2254 patients who were followed up for 4 years. Obesity was classified as a body mass index ≥30 and overweight as a body mass index of 25.0-29.9. Central obesity was defined as waist circumference ≥88 cm for women and ≥102 cm for men. Independent predictors of total and cardiac mortality were assessed in a multivariate Cox model adjusted for confounding variables. Results: Obesity was present in 35% of patients, overweight in 43%, and central obesity in 60%. Body mass index and waist circumference were independent predictors of lower total mortality: hazard ratio =0.84 (P<.001) and hazard ratio = 0.97 (P=.01), respectively, and lower cardiac death (body mass index, hazard ratio =0.84, P<.001; waist circumference, hazard ratio =0.97, P=.01). The interaction between body mass index and waist circumference (hazard ratio =1.001, P<.01) showed that the protective effect of body mass index was lost in patients with a waist circumference >120 cm. Conclusions: Mortality was significantly lower in patients with a high body mass index and waist circumference. The results also showed that this protection was lost when these indicators over a certain limit. © 2013 Sociedad Española de Cardiología.
Original languageEnglish
Pages (from-to)101-106
JournalRevista Espanola de Cardiologia
Volume67
Issue number2
DOIs
Publication statusPublished - 1 Feb 2014

Keywords

  • Body mass index
  • Heart failure
  • Multicenter study
  • Obesity paradox
  • Prognosis
  • Waist circumference

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