Prognostic factors of colorectal cancer lung metastases

Núria Prenafeta Claramunt, Vicenç Artigas Raventós, Guillermo Gómez Sebastián, Elisabeth Martínez Téllez, Josep Belda Sanchís

    Research output: Contribution to journalArticleResearchpeer-review

    1 Citation (Scopus)


    Introduction: Colorectal cancer is the third most common neoplasia and the second cause of death due to cancer in developed countries. Approximately 10% of patients with this diagnosis develop lung metastases, although only 2-4% of them have lung metastases as the only extension location. Objective: To study the prognostic factors of colorectal cancer lung metastases. Patients and methods: A retrospective observational study was conducted on 30 patients with colorectal cancer lung metastases who were operated on in our hospital between January 2003 and December 2007. Results: Of the 30 patients who received surgery, 19 were males (63%) and 11 were female (37%), with a mean age of 63.37 years (range 35-82 years). The mean overall survival was 36.64 months (range 18.58-54.70 months).A total of 13 pre-, intra-, and postoperative parameters were used in the statistical analysis. In the univariate analysis, the number of metastases greater than 3 (P=.051), whether they were bilateral (P=.001), or bilobar (P<.001), were statistically significant factors of a poor prognosis. In the multivariate analysis, only being bilobar was shown to be a statistically significant factor of a poor prognosis (P=.005). Conclusions: In our patient series affected by colorectal carcinoma lung metastases, the number of metastases greater than three, whether they are bilobar and bilateral, are factors of a poor prognosis.These factors should be taken into account in the follow-up of these patients, although prospective studies with a larger number of patients are required to confirm these findings. © 2011 AEC.
    Original languageEnglish
    Pages (from-to)169-175
    JournalCirugia Espanola
    Issue number3
    Publication statusPublished - 1 Mar 2012


    • Colorectal cancer
    • Lung metastases
    • Prognostic factors


    Dive into the research topics of 'Prognostic factors of colorectal cancer lung metastases'. Together they form a unique fingerprint.

    Cite this