Arabitol was produced from glucose by Hansenula polymorpha DSM 70277. Some of the factors influencing production of polyols were studied: temperature, aeration, osmotic pressure and nitrogen concentration. The best results (18.8 g/l of arabitol-no other polyol was detected-after 60 h of cultivation with a yield of 0.14 g · arabitol per g · glucose utilized) were obtained for a fermentation done in fed-batch mode, with a glucose concentration always less than 30 g/l, at 45°C, pH 4.8, stirring rate 1000 rpm and using air at 1 vvm in a 2l fermentor. Neither ethanol nor acetate were detected in this experiment. © 1990.
|Journal||Journal of Fermentation and Bioengineering|
|Publication status||Published - 1 Jan 1990|