Primitive neuroectodermal tumor of the central nervous system with glial differentiation: A FISH study of an adult case

F. Alameda; J. Lloreta; A. Ariza; M. Salido; B. Espinet; T. Baro; G. Garcia-Fructoso; E. Galito; A. Munne; F. F. Cruz Sanchez; F. Sole; S. Serrano

doi:10.5414/NPP26012

Primitive neuroectodermal tumor of the central nervous system with glial differentiation: A FISH study of an adult case

F. Alameda, J. Lloreta, A. Ariza, M. Salido, B. Espinet, T. Baro, G. Garcia-Fructoso, E. Galito, A. Munne, F. F. Cruz Sanchez, F. Sole, S. Serrano

Research output: Contribution to journal › Article › Research › peer-review

Abstract

Primitive neuroectodermal tumors (PNETs) of the central nervous system (CNS), a rare occurrence in adults, may show glial differentiation and can be misinterpreted as pure astrocytic neoplasms. Few fluorescence in situ hybridization (FISH) studies have been carried out on these tumors; isochromosome 17q was found to be the major chromosomal abnormality. We present the case of an adult in which we performed a FISH study of both the glial and neuronal components. A complex array of FISH changes, not including an isochromosome 17q were identified. ©2007 Dustri-Verlag Dr. K. Feistle.

Original language	English
Pages (from-to)	12-16
Journal	Clinical Neuropathology
Volume	26
Issue number	1
DOIs	https://doi.org/10.5414/NPP26012
Publication status	Published - 1 Jan 2007

Keywords

CNS tumors
FISH
Isochromosome 17
PNET

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title = "Primitive neuroectodermal tumor of the central nervous system with glial differentiation: A FISH study of an adult case",

abstract = "Primitive neuroectodermal tumors (PNETs) of the central nervous system (CNS), a rare occurrence in adults, may show glial differentiation and can be misinterpreted as pure astrocytic neoplasms. Few fluorescence in situ hybridization (FISH) studies have been carried out on these tumors; isochromosome 17q was found to be the major chromosomal abnormality. We present the case of an adult in which we performed a FISH study of both the glial and neuronal components. A complex array of FISH changes, not including an isochromosome 17q were identified. {\textcopyright}2007 Dustri-Verlag Dr. K. Feistle.",

keywords = "CNS tumors, FISH, Isochromosome 17, PNET",

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T1 - Primitive neuroectodermal tumor of the central nervous system with glial differentiation: A FISH study of an adult case

AU - Alameda, F.

AU - Lloreta, J.

AU - Ariza, A.

AU - Salido, M.

AU - Espinet, B.

AU - Baro, T.

AU - Garcia-Fructoso, G.

AU - Galito, E.

AU - Munne, A.

AU - Cruz Sanchez, F. F.

AU - Sole, F.

AU - Serrano, S.

PY - 2007/1/1

Y1 - 2007/1/1

N2 - Primitive neuroectodermal tumors (PNETs) of the central nervous system (CNS), a rare occurrence in adults, may show glial differentiation and can be misinterpreted as pure astrocytic neoplasms. Few fluorescence in situ hybridization (FISH) studies have been carried out on these tumors; isochromosome 17q was found to be the major chromosomal abnormality. We present the case of an adult in which we performed a FISH study of both the glial and neuronal components. A complex array of FISH changes, not including an isochromosome 17q were identified. ©2007 Dustri-Verlag Dr. K. Feistle.

AB - Primitive neuroectodermal tumors (PNETs) of the central nervous system (CNS), a rare occurrence in adults, may show glial differentiation and can be misinterpreted as pure astrocytic neoplasms. Few fluorescence in situ hybridization (FISH) studies have been carried out on these tumors; isochromosome 17q was found to be the major chromosomal abnormality. We present the case of an adult in which we performed a FISH study of both the glial and neuronal components. A complex array of FISH changes, not including an isochromosome 17q were identified. ©2007 Dustri-Verlag Dr. K. Feistle.

KW - CNS tumors

KW - FISH

KW - Isochromosome 17

KW - PNET

U2 - 10.5414/NPP26012

DO - 10.5414/NPP26012

M3 - Article

SN - 0722-5091

VL - 26

SP - 12

EP - 16

JO - Clinical Neuropathology

JF - Clinical Neuropathology

IS - 1

ER -

Primitive neuroectodermal tumor of the central nervous system with glial differentiation: A FISH study of an adult case

Abstract

Keywords

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