Primary hyperoxaluria (L-glyceric aciduria) in a cat

Davide De Lorenzi, Marco Bernardini, Marti Pumarola

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)


A 7-month-old, male European cat was examined because of weakness and inappetence. The cat was dehydrated, polypnoeic and severely weak. Severe, generalised muscle atrophy was present. Spinal reflexes were all decreased to absent. Blood analysis and urinalysis showed several abnormalities, including intermittent hyperoxaluria. The l -gliceric acid concentration was remarkably increased. Electrodiagnostic tests of the peripheral nervous system were abnormal. At necropsy, generalised muscle atrophy was observed. Microscopically, both kidneys showed intraluminal birefringent oxalate crystals. Motor neuron degeneration and accumulation of neurofilaments were observed in the axons of the spinal motor neurons. © ESFM and AAFP. Published by Elsevier Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)357-361
JournalJournal of Feline Medicine and Surgery
Publication statusPublished - 1 Dec 2005


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