Primary central white matter degeneration in old dogs

Marti Pumarola Batlle, I. Ferrer, R. Rivera, M. J. Zújar, F. Cruz-Sánchez, A. Vidal

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    29 Citations (Scopus)


    Degeneration of the central white matter is described in old dogs. The presence of ubiquitin-immunoreactive free granules and intracytoplasmic globules in glial cells and macrophages, together with galactocerebroside-immunoreactive precipitates and lipofuscin storage, point to the likelihood of a primary myelin degeneration with deposits of non-degraded ubiquitin-protein conjugates and complex galactolipids. © 1993 Springer-Verlag.
    Original languageEnglish
    Pages (from-to)172-175
    JournalActa Neuropathologica
    Issue number2
    Publication statusPublished - 1 Jul 1993


    • Aging
    • Galactocerebroside
    • Ubiquitin
    • White matter


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