TY - JOUR
T1 - Preventive treatments for breast cancer :
T2 - recent developments
AU - Alés-Martínez, José Enrique
AU - Ruiz, Amparo
AU - Chacón, José Ignacio
AU - Lluch Hernández, A.
AU - Ramos Vázquez, Manuel
AU - Córdoba, Octavi
AU - Aguirre, Elena
AU - Barnadas i Molins, Agustí
AU - Jara Sánchez, Carlos
AU - González Santiago, Santiago
AU - Plazaola, A.
AU - Florián, Jesús
AU - Andrés Conejero, Raquel
AU - Sánchez Rovira, Pedro
AU - Frau, Adolfo
PY - 2015
Y1 - 2015
N2 - Breast cancer is a burden for western societies, and an increasing one in emerging economies, because of its high incidence and enormous psychological, social, sanitary and economic costs. However, breast cancer is a preventable disease in a significant proportion. Recent developments in the armamentarium of effective drugs for breast cancer prevention (namely exemestane and anastrozole), the new recommendation from the National Institute for Health and Care Excellence to use preventative drugs in women at high risk as well as updated Guidelines from the US Preventive Services Task Force and the American Society of Clinical Oncology should give renewed momentum to the pharmacological prevention of breast cancer. In this article we review recent major developments in the field and examine their ongoing repercussion for breast cancer prevention. As a practical example, the potential impact of preventive measures in Spain is evaluated and a course of practical actions is delineated.
AB - Breast cancer is a burden for western societies, and an increasing one in emerging economies, because of its high incidence and enormous psychological, social, sanitary and economic costs. However, breast cancer is a preventable disease in a significant proportion. Recent developments in the armamentarium of effective drugs for breast cancer prevention (namely exemestane and anastrozole), the new recommendation from the National Institute for Health and Care Excellence to use preventative drugs in women at high risk as well as updated Guidelines from the US Preventive Services Task Force and the American Society of Clinical Oncology should give renewed momentum to the pharmacological prevention of breast cancer. In this article we review recent major developments in the field and examine their ongoing repercussion for breast cancer prevention. As a practical example, the potential impact of preventive measures in Spain is evaluated and a course of practical actions is delineated.
KW - Aromatase inhibitors
KW - BRCA
KW - Breast cancer
KW - Breast cancer prevention
KW - GEICAM
KW - Pharmacological prevention
UR - http://dialnet.unirioja.es/servlet/articulo?codigo=5024291
U2 - 10.1007/s12094-014-1250-2
DO - 10.1007/s12094-014-1250-2
M3 - Review article
C2 - 25445174
SN - 1699-3055
VL - 17
SP - 257
EP - 263
JO - Clinical & translational oncology
JF - Clinical & translational oncology
IS - 4
ER -