© Author(s) 2016. Background: The current prevalence of esophagitis in southern Europe is unknown. In addition, the risk factors for reflux esophagitis are not fully understood. Objective: The objective of this article is to assess the prevalence and risk factors for esophagitis in Spain. Methods: A prospective, observational, cross-sectional, multicenter study (PRESS study) was conducted among 31 gastrointestinal endoscopy units throughout Spain. A total of 1361 patients undergoing upper gastrointestinal endoscopy were enrolled. Sociodemographic, clinical and treatment data were recorded. Results: A total of 95% of patients were Caucasian and 52% were male (mean age: 53±17 years). The most frequent symptoms prompting endoscopy were heartburn (40%), regurgitation (26%) and dysphagia (15%). Fifty-four percent of patients undergoing endoscopy were receiving proton pump inhibitor (PPI) treatment. Esophagitis (mainly mild-moderate) was present in 154 (12.4%) patients. The severe form was recorded in only 11 (0.8%) patients. Multivariate analysis results indicated that the likelihood of esophagitis was higher in men (OR=1.91, 95% CI=1.31–2.78), in patients with high GERDQ scores (OR=1.256, 95% CI=1.176–1.343), weight increase (OR=1.014, 95% CI=1.003–1.025) and high alcohol consumption (OR=2.49, 95% CI=1.16–5.36). Conclusion: Severe esophagitis is a rare finding in the Spanish population. Male gender, high GERD-Q score, weight increase and high alcohol consumption are main risk factors for its appearance.
- Barrett’s esophagus
- Gastro-esophageal reflux disease (GERD)
- Gastrointestinal symptoms
- Hiatal hernia
- Nonsteroidal anti-inflammatory drugs (NSAID)
- Severe esophagitis