TY - JOUR
T1 - Prevalence of Hepatitis E Virus (HEV) Antibodies in Mexican Pigs
AU - Merino-Ramos, Teresa
AU - Martín-Acebes, Miguel A.
AU - Casal, Jordi
AU - Saiz, Juan Carlos
AU - Loza-Rubio, Elizabeth
PY - 2016/6/1
Y1 - 2016/6/1
N2 - © 2016, Springer Science+Business Media New York. The hepatitis E virus (HEV) is the causative agent of Hepatitis E, an enterically transmitted disease. HEV infections in pigs and humans have been reported worldwide, but data from Mexico are scarce. In the present study, the prevalence of anti-HEV IgG antibodies was investigated in a quite large number of swine from Mexico by means of an ELISA based on a recombinant open reading frame 2 protein of HEV genotype 3. Serum samples from 683 healthy pigs (1–48 months old), collected during 2010–2013 in 109 herds from 48 municipalities located in 9 states in the centre of the country were assayed. A 30.75 % (210/683) of the sera tested were positive, and they were distributed along all the states included in the study. The prevalence of anti-HEV antibodies varied widely between municipalities and herds, and it was higher in pigs 4–6 months of age. No relationships were detected between seroprevalences and farm characteristics. Forty individual faecal samples were analysed by RT-PCR and all resulted negative. These data indicate that HEV infection is widespread in Mexican pigs; thus, representing a potential zoonotic risk for humans.
AB - © 2016, Springer Science+Business Media New York. The hepatitis E virus (HEV) is the causative agent of Hepatitis E, an enterically transmitted disease. HEV infections in pigs and humans have been reported worldwide, but data from Mexico are scarce. In the present study, the prevalence of anti-HEV IgG antibodies was investigated in a quite large number of swine from Mexico by means of an ELISA based on a recombinant open reading frame 2 protein of HEV genotype 3. Serum samples from 683 healthy pigs (1–48 months old), collected during 2010–2013 in 109 herds from 48 municipalities located in 9 states in the centre of the country were assayed. A 30.75 % (210/683) of the sera tested were positive, and they were distributed along all the states included in the study. The prevalence of anti-HEV antibodies varied widely between municipalities and herds, and it was higher in pigs 4–6 months of age. No relationships were detected between seroprevalences and farm characteristics. Forty individual faecal samples were analysed by RT-PCR and all resulted negative. These data indicate that HEV infection is widespread in Mexican pigs; thus, representing a potential zoonotic risk for humans.
KW - ELISA
KW - HEV
KW - Mexico
KW - Pigs
KW - RNA
KW - Seroprevalence
U2 - 10.1007/s12560-016-9231-y
DO - 10.1007/s12560-016-9231-y
M3 - Article
SN - 1867-0334
VL - 8
SP - 156
EP - 159
JO - Food and Environmental Virology
JF - Food and Environmental Virology
IS - 2
ER -
