Prevalence and clinical characteristics of HIV type 1-infected patients receiving dialysis in Spain: Results of a Spanish survey in 2006: GESIDA 48/05 study

J.-C. Trullàs, G. Barril, F. Cofan, A. Moreno, A. Cases, M. Fernandez-Lucas, J. Martinez-Ara, M. Ceballos, J. Garcia-De-Diego, M.-L. Muñiz, J. Molina, A. Martínez-Castelao, J. González-Garcia, J.-M. Miró, A. Mazuecos, J. Burgos, Ferran Torres

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25 Citations (Scopus)

Abstract

End-stage renal diseases (ESRD) are becoming more frequent in HIV-infected patients. In Europe there is little information about HIV-infected patients on dialysis. A cross-sectional multicenter survey in 328 Spanish dialysis units was conducted in 2006. Information from 14,876 patients in dialysis was obtained (81.6% of the Spanish dialysis population). Eighty-one were HIV infected (0.54%; 95% CI, 0.43-0.67), 60 were on hemodialysis, and 21 were on peritoneal dialysis. The mean (range) age was 45 (28-73) years. Seventy-two percent were men and 33% were former drug users. The mean (range) time of HIV infection was 11 (1-27) years and time on dialysis was 4.6 (0.4-25) years. ESRD was due to glomerulonephritis (36%) and diabetes (15%). HIV-associated nephropathy was not reported. Eighty-five percent were on HAART, 76.5% had a CD4 T cell count above 200 cells, and 73% had undetectable viral load. Thirty-nine percent of patients met criteria for inclusion on the renal transplant (RT) waiting list but only 12% were included. Sixty-one percent had HCV coinfection. HCV-coinfected patients had a longer history of HIV, more previous AIDS events, parenteral transmission as the most common risk factor for acquiring HIV infection, and less access to the RT waiting list (p < 0.05). The prevalence of HIV infection in Spanish dialysis units in 2006 was 0.54% HCV coinfection was very frequent (61%) and the percentage of patients included on the Spanish RT waiting list was low (12%). © 2008 Mary Ann Liebert, Inc.
Original languageEnglish
Pages (from-to)1229-1235
Number of pages7
JournalAIDS Research and Human Retroviruses
Volume24
Issue number10
DOIs
Publication statusPublished - Oct 2008

Keywords

  • adult
  • article
  • CD4+ T lymphocyte
  • controlled study
  • dialysis
  • female
  • health survey
  • human
  • Human immunodeficiency virus 1
  • Human immunodeficiency virus infection
  • kidney graft
  • major clinical study
  • male
  • prevalence
  • priority journal
  • Spain
  • Adult
  • Aged
  • Antiretroviral Therapy, Highly Active
  • CD4 Lymphocyte Count
  • Cross-Sectional Studies
  • Dialysis
  • Female
  • Hepatitis C
  • HIV Infections
  • Humans
  • Kidney Failure
  • Male
  • Middle Aged
  • Prevalence
  • Viral Load

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