Preparation, antimicrobial evaluation, and mutagenicity of [2- hydroxyaryl]-[1-methyl-5-nitro-1H-2-imidazolyl]methanols, [5-tert-butyl-2- methylaminophenyl]-[1-methyl-5-nitro-1H-2-imidazolyl] methanol, and [2- hydroxyaryl]-[1-methyl-5-nitro-1H-2-imidazolyl] ketones

Y. Arredondo, M. Moreno-Mañas, R. Pleixats, C. Palacín, M. M. Raga, J. M. Castelló, J. A. Ortiz

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Abstract

Efficient preparations of the titled compounds are described, their antimicrobial activity and mutagenic properties being evaluated. Some of the studied compounds are nonmutagenic and present a MIC as low as some of the usual standards in the field.
Original languageEnglish
Pages (from-to)1959-1968
JournalBioorganic and Medicinal Chemistry
Volume5
Issue number10
DOIs
Publication statusPublished - 1 Oct 1997

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