TY - JOUR
T1 - Preparation and behavior of (R)- and (S)-2,2,2-trifluoro-1-(1-pyrenyl)ethanol as chiral solvating agents: Study of the diastereomeric association by Job's plots, intermolecular NOE and binding constants
AU - Muñoz, Anna
AU - Virgili, Albert
PY - 2002/8/1
Y1 - 2002/8/1
N2 - Racemic 2,2,2-trifluoro-1-(1-pyrenyl)ethanol 2, was prepared and the (R)- and (S)-enantiomers obtained by preparative chiral HPLC. The behavior of these compounds as chiral solvating agents is studied with mixtures of several enantiomeric aromatic alcohols and amines. The non-linear distribution of aromatic rings in the pyrene appears to enhance the enantiodiscrimination capacity. © 2002 Elsevier Science Ltd. All rights reserved.
AB - Racemic 2,2,2-trifluoro-1-(1-pyrenyl)ethanol 2, was prepared and the (R)- and (S)-enantiomers obtained by preparative chiral HPLC. The behavior of these compounds as chiral solvating agents is studied with mixtures of several enantiomeric aromatic alcohols and amines. The non-linear distribution of aromatic rings in the pyrene appears to enhance the enantiodiscrimination capacity. © 2002 Elsevier Science Ltd. All rights reserved.
U2 - 10.1016/S0957-4166(02)00370-1
DO - 10.1016/S0957-4166(02)00370-1
M3 - Article
VL - 13
SP - 1529
EP - 1534
IS - 14
ER -