Preoperative MRI of pure intraductal breast carcinoma - A valuable adjunct to mammography in assessing cancer extent

Gorane Santamaria*, Martin Velasco, Blanca Farrus, Gabriel Zanon, Pedro Luis Fernandez

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)

Abstract

The aim of the study was to evaluate the contribution of preoperative breast magnetic resonance imaging (MRM) as an adjunct to mammography in assessing extent of pure ductal carcinoma in situ (DCIS) and to relate magnetic resonance imaging (MRI) findings to histopathological features. A retrospective analysis was conducted of 86 histologically proven cases of pure DCIS of the breast. Two experienced radiologists with knowledge of clinical and histopathological findings at the time of the review evaluated mammographic and preoperative MRI results by consensus. Compared to histopathology, mammography or MRM alone underestimated DCIS extent in 18.6% and 31.4% of cases, respectively. When both imaging modalities were considered, DCIS extent was underestimated in 8% of cases. Combined use of mammography and MRM revealed good agreement with histopathology to assess DCIS extent (kappa = 0.439; P <0.001). MR enhancement of DCIS was related to histologic size (P = 0.011).

Original languageEnglish
Pages (from-to)186-194
Number of pages9
JournalThe Breast. PMID: 14965564.
Volume17
Issue number2
DOIs
Publication statusPublished - Apr 2008

Keywords

  • magnetic resonance imaging
  • mammography
  • carcinoma
  • intraductal
  • noninfiltrating
  • breast
  • IN-SITU
  • MANAGEMENT
  • ULTRASONOGRAPHY
  • ENHANCEMENT
  • DISEASE
  • LESIONS

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