Prematurity and ADHD in Childhood: An Observational Register-Based Study in Catalonia

J. Perapoch, R. Vidal, A. Gómez-Lumbreras, E. Hermosilla, L. Riera, J. Cortés, M. C. Céspedes, J. A. Ramos-Quiroga, R. Morros

Research output: Contribution to journalArticleResearch

2 Citations (Scopus)

Abstract

Objective: To evaluate the association between prematurity (by the gestational week [gw]) and ADHD during childhood. Method: Observational, matched cohort study using data from children born in a tertiary-level hospital (Hospital Universitari Vall d’Hebron, Catalonia, Spain) during 1995-2007 and data from the Information System for the Development of Research in Primary Health Care (SIDIAP database, Catalonia, Spain). Results: Prevalence of ADHD increases as gestational age decreases, 12.7% for those born ≤28 gw, compared to 3.2% for those born after the 37 gw. The risk of developing ADHD in the non-premature children tends to increase as the gw decreases (35-36 gw, hazard ratio [HR] = 1.70, 95% confidence interval [CI] [1.19, 2.44]; 33-34 gw, HR = 3.38, 95% CI [2.08, 5.50]; 29-32 gw, HR = 2.37, 95% CI [1.54, 3.63]; and ≤28 gw, HR = 5.57, 95% CI [2.49, 12.46]) Conclusion: Being born preterm is associated with a risk of developing ADHD, also in late preterm children (35-36 gw). Attention when taking care of these infants regarding their mental health must be made.
Original languageEnglish
Article number1087054719864631
Pages (from-to)1087054719864631
Number of pages9
JournalJournal of Attention Disorders
DOIs
Publication statusPublished - 14 Aug 2019

Keywords

  • AGE-CHILDREN
  • ATTENTION-DEFICIT/HYPERACTIVITY DISORDER
  • BEHAVIORAL SYMPTOMS
  • CHILDREN BORN
  • DEFICIT HYPERACTIVITY DISORDER
  • LOW-BIRTH-WEIGHT
  • PRETERM BIRTH
  • RISK-FACTORS
  • SCHOOL-AGE
  • UNITED-STATES
  • attention deficit disorder with hyperactivity
  • child
  • premature
  • psychotropic drugs

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