Preliminary study of the incidence of disomy in sperm fractions after MicroSort flow cytometry

F. Vidal, J. Blanco, E. F. Fugger, K. Keyvanfar, M. Norton, J. D. Schulman, J. Egozcue

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12 Citations (Scopus)

Abstract

Using triple colour fluorescent in-situ hybridization (FISH) we have evaluated, on a blind basis, the disomy level for chromosome 21 and the sex chromosomes in flow cytometric sorted sperm samples. There were no statistically significant differences in the disomy rates when comparing the sorted samples (either for X- or Y-bearing spermatozoa) with non-sorted samples. There were no diploid spermatozoa observed in any sample group after MicroSort® processing.
Original languageEnglish
Pages (from-to)2987-2990
JournalHuman Reproduction
Volume14
DOIs
Publication statusPublished - 1 Jan 1999

Keywords

  • Chromosome 21 disomies
  • Flow cytometry
  • Fluorescence in-situ hybridization
  • Sperm sex selection

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