Pregnancy as an opportunity to diagnose human-immunodeficiency virus immigrant women in Catalonia

Antoni Soriano-Arandes, Antoni Noguera-Julian, Mónica López-Lacort, Pere Soler-Palacín, Antonio Mur, María Méndez, Lluís Mayol, Teresa Vallmanya, Jesús Almeda, Dolors Carnicer-Pont, Jordi Casabona, Claudia Fortuny

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Abstract

© 2016 Elsevier España, S.L.U. and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica Introduction Mother-to-child transmission (MTCT) is relevant in the global epidemiology of human-immunodeficiency virus (HIV), as it represents the main route of infection in children. The study objectives were to determine the rate of HIV-MTCT and its epidemiological trend between the Spanish-born and immigrant population in Catalonia in the period 2000-2014. Methods A prospective observational study of mother-child pairs exposed to HIV, treated in 12 hospitals in Catalonia in the period 2000-2014. HIV-MTCT rate was estimated using a Bayesian logistic regression model. R and WinBUGS statistical software were used. Results The analysis included 909 pregnant women, 1,009 pregnancies, and 1,032 children. Data on maternal origin was obtained in 79.4% of women, of whom 32.7% were immigrants, with 53.0% of these from sub-Saharan Africa. The overall HIV-MTCT rate was 1.4% (14/1,023; 95% CI; 0.8-2.3). The risk of MTCT-HIV was 10-fold lower in women with good virological control (P =.01), which was achieved by two-thirds of them. The proportion of immigrants was significantly higher in the period 2008-2014 (P <.0001), for the HIV-diagnosis (P <.0001), and antiretroviral administration (P=.02) during pregnancy, and for undetectable viral load next to delivery (P <.001). There were no differences in the rate of MTCT-HIV among Spanish-born and immigrant women (P =.6). Conclusions There is a gradual increase in HIV pregnant immigrants in Catalonia. Although most immigrant women were diagnosed during pregnancy, the rate of MTCT-HIV was no different from the Spanish-born women.
Original languageEnglish
Pages (from-to)9-15
JournalEnfermedades Infecciosas y Microbiologia Clinica
Volume36
Issue number1
DOIs
Publication statusPublished - 1 Jan 2018

Keywords

  • Epidemiology
  • Human-immunodeficiency syndrome
  • Immigration
  • Pregnancy
  • Public health
  • Vertical transmission

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    Soriano-Arandes, A., Noguera-Julian, A., López-Lacort, M., Soler-Palacín, P., Mur, A., Méndez, M., Mayol, L., Vallmanya, T., Almeda, J., Carnicer-Pont, D., Casabona, J., & Fortuny, C. (2018). Pregnancy as an opportunity to diagnose human-immunodeficiency virus immigrant women in Catalonia. Enfermedades Infecciosas y Microbiologia Clinica, 36(1), 9-15. https://doi.org/10.1016/j.eimc.2016.07.011