Pregnancy and congenital heart disease

Begoña Manso García, Ferran Gran, Antonia Pijuan, Gemma Giralt, Queralt Ferrer, Pedro Betrián, Dimpna Albert, Ferran Rosés, Núria Rivas, Montserrat Parra, Josep Girona, Inmaculada Farran, Jaume Casalàáliga

    Research output: Contribution to journalArticleResearchpeer-review

    13 Citations (Scopus)

    Abstract

    Introduction and objectives. Since the creation of the Adult Congenital Heart Disease Units and of the High Obstetric Risk Units, there has been increasing interest in hemodynamic and obstetric outcomes in pregnant woman with congenital heart disease. Methods. Retrospective descriptive study of 56 women with congenital heart disease aged (mean [range]) 25 (18-40) years, who experienced a total of 84 pregnancies between January 1992 and August 2006. The women were divided into 3 pregnancy risk groups: A, low-risk; B, moderate-risk; and C, high-risk. Results. The incidence of complications during pregnancy was 1.6%, 15%, and 20% in groups A, B, and C, respectively; the incidence during the puerperium was 2%, 23%, and 50%, respectively; and maternal mortality was 0%, 7.6%, and 25%, respectively. Overall, 69 children were born, and the prematurity rates in the 3 groups were 11%, 15%, and 100%, respectively. The following risk factors were studied: pulmonary hypertension, cyanosis, arrhythmia, left ventricular outflow tract obstruction, right ventricular dilatation, systemic right ventricle, and anticoagulation therapy. The risk factor most significantly associated with maternal or fetal morbidity, or mortality was found to be pulmonary hypertension. Conclusions. Risk stratification in pregnant women with congenital heart disease provides prognostic information that can help multidisciplinary teams to target care to achieve the best results.
    Original languageEnglish
    Pages (from-to)236-243
    JournalRevista Espanola de Cardiologia
    Volume61
    Issue number3
    DOIs
    Publication statusPublished - 1 Jan 2008

    Keywords

    • Congenital heart disease
    • Pregnancy
    • Risk factor

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