We assessed whether pregnancy after breast cancer in patients younger than 36 years of age affects the prognosis. Of 115 women with breast cancer followed for a mean of 6 years, 18 became pregnant (median time between diagnosis and the first pregnancy 44.5 months). Voluntary interruption of pregnancy was decided by 8 (44.4%) women. Significant differences in prognostic factors between pregnant and non-pregnant women were not observed. Pregnant women showed a lower frequency of positive estrogen receptors (41%) than non-pregnant (64%) (P = 0.06). At 5 years of follow-up, 100% of women in the pregnant group and 80% in the non-pregnant group were alive. The percentages of disease-free women were 94% and 64%, respectively (P = 0.009). Breast cancer patients presented a high number of unwanted pregnancies. Pregnancy after breast cancer not only did not adversely affect prognosis of the neoplasm but also may have a protective effect. © 2011 Elsevier Ltd.
- Breast neoplasms
- Retrospective studies
- Treatment outcome
Córdoba, O., Bellet, M., Vidal, X., Cortés, J., Llurba, E., Rubio, I. T., & Xercavins, J. (2012). Pregnancy after treatment of breast cancer in young women does not adversely affect the prognosis. Breast, 21(3), 272-275. https://doi.org/10.1016/j.breast.2011.10.001