Pregnancy after treatment of breast cancer in young women does not adversely affect the prognosis

Octavi Córdoba, Meritxell Bellet, Xavier Vidal, Javier Cortés, Elisa Llurba, Isabel T. Rubio, Jordi Xercavins

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16 Citations (Scopus)


We assessed whether pregnancy after breast cancer in patients younger than 36 years of age affects the prognosis. Of 115 women with breast cancer followed for a mean of 6 years, 18 became pregnant (median time between diagnosis and the first pregnancy 44.5 months). Voluntary interruption of pregnancy was decided by 8 (44.4%) women. Significant differences in prognostic factors between pregnant and non-pregnant women were not observed. Pregnant women showed a lower frequency of positive estrogen receptors (41%) than non-pregnant (64%) (P = 0.06). At 5 years of follow-up, 100% of women in the pregnant group and 80% in the non-pregnant group were alive. The percentages of disease-free women were 94% and 64%, respectively (P = 0.009). Breast cancer patients presented a high number of unwanted pregnancies. Pregnancy after breast cancer not only did not adversely affect prognosis of the neoplasm but also may have a protective effect. © 2011 Elsevier Ltd.
Original languageEnglish
Pages (from-to)272-275
Issue number3
Publication statusPublished - 1 Jun 2012


  • Breast neoplasms
  • Pregnancy
  • Retrospective studies
  • Treatment outcome


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