Potential Benefit of Lymph Node Dissection During Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma: A Systematic Review by the European Association of Urology Guidelines Panel on Non–muscle-invasive Bladder Cancer

Jose Luis Dominguez-Escrig, Benoit Peyronnet, Thomas Seisen, Harman M. Bruins, Cathy Yuhong Yuan, Marko Babjuk, Andreas Böhle, Maximilian Burger, Eva M. Compérat, Paolo Gontero, Thomas Lam, Steven MacLennan, Hugh Mostafid, Joan Palou, Bas W.G. van Rhijn, Richard J. Sylvester, Richard Zigeuner, Shahrokh F. Shariat, Morgan Rouprêt

    Research output: Contribution to journalReview articleResearchpeer-review

    26 Citations (Scopus)

    Abstract

    © 2017 European Association of Urology Upper tract urothelial carcinoma (UTUC) represents an infrequent malignancy that carries a poor prognosis, with a high risk of lymphatic spread and subsequent disease progression. Template-based, complete lymph node dissection (LND) improves cancer-specific survival in patients with high-stage (≥pT2) UTUC and reduces the risk of local recurrence. LND improves survival in patients with high-stage disease of the renal pelvis if it is performed according to an anatomical template-based approach.
    Original languageEnglish
    Pages (from-to)224-241
    JournalEuropean Urology Focus
    Volume5
    Issue number2
    DOIs
    Publication statusPublished - 1 Mar 2019

    Keywords

    • Metastasis
    • Nodes
    • Recurrence
    • Renal pelvis
    • Survival
    • Ureter
    • Urothelial carcinoma

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