Porcine intramuscular fat content and composition are regulated by quantitative trait loci with muscle-specific effects

R. Quintanilla, R. N. Pena, D. Gallardo, A. Cánovas, O. Ramírez, I. Díaz, J. L. Noguera, M. Amills

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44 Citations (Scopus)

Abstract

Intramuscular fat (IMF) storage is a biological process with a strong impact on nutritional and technological properties of meat and also with rel- evant consequences on human health. The genetic ar- chitecture of IMF content and composition phenotypes has been thoroughly studied in pigs through the iden- tification of QTL and the estimation of genetic param- eters. A question that has not been elucidated yet is if the genetic determinants of IMF-related phenotypes are muscle specific or, conversely, have broad effects on the whole skeletal muscle compartment. We have ad- dressed this question by generating lipid QTL maps for 2 muscles with a high commercial value, gluteus medius (GM) and longissimus thoracis et lumborum (LTL), in a Duroc commercial population (n = 350). Our data support a lack of concordance between the GM and LTL QTL maps, suggesting that the effects of poly- morphisms influencing IMF, cholesterol, and fatty acid contents are modulated to some extent by complex spa- tial factors related to muscle location, metabolism, and function. These results have important implications on the implementation of genomic selection schemes aimed to improve the lipid profile of swine meat. © 2011 American Society of Animal Science, All rights reserved.
Original languageEnglish
Pages (from-to)2963-2971
JournalJournal of Animal Science
Volume89
DOIs
Publication statusPublished - 1 Oct 2011

Keywords

  • Fatty acid profile
  • Genetics of muscle lipids
  • Intramuscular fat
  • Pig
  • Quantitative trait locus

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