Plasma lipids and their fatty acid composition in multiple sclerosis

X. Navarro, R. Segura

    Research output: Contribution to journalArticleResearchpeer-review

    16 Citations (Scopus)

    Abstract

    ABSTRACT‐ We report an extensive study of the plasma lipid profile and fatty acid composition in 61 multiple sclerosis (MS) patients compared with 61 normal subjects. The main abnormality in the MS was a reduction in the proportion of linoleic and arachidonic acids mostly evident in the HDL and in the cholesteryl esters fraction, with a compensatory increase in saturated acids. The fatty acid abnormalities correlated with the duration of the disease and the degree of disability. Thus, in the MS patients studied there was a deficiency in essential fatty acids, although this metabolic abnormality does not seem specific to MS. Copyright © 1988, Wiley Blackwell. All rights reserved
    Original languageEnglish
    Pages (from-to)152-157
    JournalActa Neurologica Scandinavica
    Volume78
    Issue number2
    DOIs
    Publication statusPublished - 1 Jan 1988

    Keywords

    • fatty acids
    • linoleic acids
    • lipids
    • multiple sclerosis

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