Physiological ICSI (PICSI) vs. conventional ICSI in couples with male factor: A systematic review

Georgina Avalos-Durán, Ana María Emilia Cañedo Del Ángel, Juana Rivero-Murillo, Jaime Enoc Zambrano-Guerrero, Esperanza Carballo-Mondragón, Miguel Ángel Checa-Vizcaíno

    Research output: Contribution to journalReview articleResearchpeer-review

    11 Citations (Scopus)

    Abstract

    © 2018, Sociedade Brasileira de Reproducao Assistida. All rights reservered. Objectives: To determine the efficacy of the physiological ICSI technique (PICSI) vs. conventional ICSI in the prognosis of couples with male factor, with respect to the following outcome measures: live births, clinical pregnancy, implantation, embryo quality, fertilization and miscarriage rates. Methods: A systematic review of the literature, extracting raw data and performing data analysis. Patient(s): Couples with the male factor, who were subjected to in-vitro fertilization. Main Outcome Measures: rates of live births, clinical pregnancy, implantation, embryo quality, fertilization and miscarriage. Results: In the systematic search, we found 2,918 studies and an additional study from other sources; only two studies fulfilled the inclusion criteria for this systematic review. The rates of live births, clinical pregnancy, implantation, embryo quality, fertilization and miscarriage were similar for both groups. Conclusion: There is no statistically significant difference between PICSI vs. ICSI, for any of the outcomes analyzed in this study. Enough information is still not available to prove the efficacy of the PICSI technique over ICSI in couples with male factor.
    Original languageEnglish
    Pages (from-to)139-147
    JournalJornal Brasileiro de Reproducao Assistida
    Volume22
    Issue number2
    DOIs
    Publication statusPublished - 1 Jan 2018

    Keywords

    • HA sperm selection
    • Hyaluronic acid
    • Male factor
    • PICSI
    • Physiological ICSI

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