Physiologic Parameters as Biomarkers: What Can We Learn from Physiologic Variables and Variation?

Ricard Ferrer, Antonio Artigas

Research output: Contribution to journalReview articleResearchpeer-review

11 Citations (Scopus)

Abstract

Sepsis generates an overwhelming host response characterized by changes in physiologic parameters. Monitoring these parameters can help identify and stratify septic patients. Recognizing sepsis early and identifying septic patients at risk of worsening are keys to successful treatment. Several studies have analyzed the independent physiologic parameters associated with the diagnosis of sepsis or bacteremia, with the development of severe sepsis or septic shock, and with mortality. Physiologic variability of heart rate and body temperature is reduced in sepsis and measuring the variability of these parameters can be useful for the diagnosis and prognosis of sepsis. © 2011 Elsevier Inc.
Original languageEnglish
Pages (from-to)229-240
JournalCritical Care Clinics
Volume27
Issue number2
DOIs
Publication statusPublished - 1 Apr 2011

Keywords

  • Body temperature
  • Heart rate
  • Physiologic variability
  • Respiratory rate
  • Sepsis
  • SIRS

Fingerprint Dive into the research topics of 'Physiologic Parameters as Biomarkers: What Can We Learn from Physiologic Variables and Variation?'. Together they form a unique fingerprint.

  • Cite this