Phospholipids in amniotic fluid and their correlation to respiratory distress syndrome and gestational age

L. Cabero, E. Giralt, P. Viscasillas

Research output: Contribution to journalArticleResearchpeer-review

Abstract

It is known that some amniotic fluid phospholipids are intimately correlated with the presence or absence of newborn respiratory distress. A study has been done concerning the amniotic fluid levels of lecithin sphingomyelin, lysolecithin and the L/S index, and their correlation with gestational age and the appearance of newborn respiratory distress. Low values of lecithin were observed in five cases of respiratory distress. The rest of the phospholipids, as well as the L/S index, were not among the lowest levels. Only three cases having lecithin values similar to those presenting respiratory distress followed a normal evolution. It has been observed that lecithin, lysolecithin and the L/S index increase progressively and significantly during gestation, while sphingomyelin does not follow this trend. The conclusion indicates that among the parameters studied, the lecithin level is the best for determining fetal pulmonary maturity.
Original languageEnglish
Pages (from-to)81-86
JournalCLIN.INVEST.GINEC.OBSTET.
Volume2
Issue number2
Publication statusPublished - 1 Jan 1975

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