Abstract
We constructed, tested and applied a tubular 5-ethyl-5-phenylbarbiturate ion-selective electrode based on tetraoctylammonium 5-ethyl-5-phenylbarbiturate dissolved in o-nitrophenyl octyl ether and immobilized on poly(vinyl chloride). The intrinsic features of the proposed electrode were assessed by using a low-dispersion single-channel flow injection analysis (FIA) system for performing repeated calibrations with sodium 5-ethyl-5-phenylbarbiturate standards, whose ionic strength was adjusted to 0.1 M with 0.033 M sodium sulfate. The determination of 5-ethyl-5- phenylbarbiturate in pharmaceutical preparations was accomplished by intercalating the proposed electrode into a twochannel FIA manifold. The results obtained were compared with those provided by the British Pharmacopoeia standard method. © 1992, The Japan Society for Analytical Chemistry. All rights reserved.
Original language | English |
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Pages (from-to) | 19-23 |
Journal | Analytical Sciences |
Volume | 8 |
Issue number | 1 |
DOIs | |
Publication status | Published - 1 Jan 1992 |
Keywords
- 5-ethyl-5-phenylbarbiturate
- Flow injection analysis
- pharmaceutical preparation
- tubular ion-selective electrode