Phenobarbital-responsive sialadenosis in dogs: Case series

Emili Alcoverro, Maria Dolores Tabar, Albert Lloret, Xavier Roura, Josep Pastor, Marta Planellas

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)


© 2015 Elsevier Inc. Phenobarbital-responsive sialadenosis (PRS) is a rare idiopathic disease in dogs. Vomiting, retching, and gulping with bilateral enlargement of the submandibular salivary glands are the more frequent clinical signs. A thorough diagnostic examination must be performed to rule out the most important systemic etiologies involved with chronic vomiting, as there is no specific test to diagnose PRS. Diagnosis is confirmed clinically by a rapid and dramatic improvement of clinical signs after instauration of phenobarbital treatment. The aim of this article is to describe the clinical presentation, diagnostic findings, and outcome of a case series of 4 dogs with presumptive PRS.
Original languageEnglish
Pages (from-to)109-112
JournalTopics in Companion Animal Medicine
Issue number4
Publication statusPublished - 1 Jan 2014


  • Phenobarbital
  • Salivary gland
  • Sialadenosis
  • Vomiting


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