Pharmacogenetics of the alcohol dehydrogenase system

Hans Jörnvall, Jan Olov Höög, Bengt Persson, Xavier Parés

Research output: Contribution to journalReview articleResearchpeer-review

51 Citations (Scopus)


Alcohol dehydrogenase (ADH) constitutes a complex enzyme system with different forms and extensive multiplicity. A combination of constant and variable properties regarding function, multiplicity and structure of ADH is highlighted for the human system and extended to ADH forms in general. Future perspectives suggest continued studies in specific directions for distinction of metabolic, regulatory and pharmacogenetic roles of ADH. Copyright (C) 2000 S. Karger AG, Basel.
Original languageEnglish
Pages (from-to)184-191
Issue number3
Publication statusPublished - 1 Jan 2000


  • Alcohol dehydrogenase isozymes
  • Biochemistry
  • Evolution
  • Pharmacogenetics
  • Regulation
  • Structure
  • Toxicol ogy


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