Phaeohyphomycosis caused by Medicopsis romeroi in solid organ transplant recipients: Report of two cases and comprehensive review of the literature

Ibai Los-Arcos, Meritxell Royuela, M. Teresa Martín-Gómez, Ana Alastruey-Izquierdo, Joana Sellarès, Manel Perelló, Lluís Castells, Cristina Dopazo, Joan Gavaldà, Oscar Len

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10 Citations (Scopus)

Abstract

© 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd Medicopsis romeroi is a melanized coelomycetous fungus, mainly found in tropical and subtropical regions and an uncommon cause of infection in solid organ transplant (SOT) recipients. We describe two cases of SOT recipients diagnosed with phaeohyphomycosis due to M romeroi and provide a comprehensive literature review. These infections should be considered in patients native to tropical countries with a localized skin and soft tissue infection. Sequencing is needed for accurate identification of uncommon melanized fungi. Surgical treatment is recommended to cure the infection and co-adjunctive oral antifungals should be considered.
Original languageEnglish
Article numbere13072
JournalTransplant Infectious Disease
Volume21
DOIs
Publication statusPublished - 1 Jun 2019

Keywords

  • dematiaceous fungi
  • melanized fungi
  • posaconazole
  • solid organ transplantation
  • voriconazole
  • Humans
  • Middle Aged
  • Male
  • Organ Transplantation/adverse effects
  • Transplant Recipients
  • Microbial Sensitivity Tests
  • Phaeohyphomycosis/diagnosis
  • Debridement
  • Ascomycota/drug effects
  • Antifungal Agents/pharmacology
  • Tropical Climate
  • Female
  • Aged
  • Retrospective Studies
  • Skin/microbiology

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