Pethidine (meperidine hydrochloride): First-line analgesic in the emergency departments?

M. L. Iglesias, M. Farré, O. Pallas, J. Pedro Botet

Research output: Contribution to journalReview articleResearchpeer-review


In the last years, the use of pethidine (meperidine hydrochloride) has been assessed by different authors. The anticholinergic activity of this agent, the long half-life of its active metabolite as well as the better knowledge of the pharmacological action, prompted a change both in the recommendation for the clinical use of this compound and in the understanding and treatment of its toxicity. Currently, it is considered a second-line analgesic in the emergency department setting.
Original languageEnglish
Pages (from-to)33-35
JournalPuesta al Dia en Urgencias, Emergencias y Catastrofes
Issue number1
Publication statusPublished - 1 Jan 2004


  • Emergency Department
  • Meperidine
  • Pethidine


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