Persistence of MRI hyperintensity of the globus pallidus in cirrhotic patients: A 2-year follow-up study

J. Kulisevsky; J. Pujol; J. Deus; C. Junqué; J. Balanzó; A. Avila; A. Capdevila

doi:10.1212/WNL.45.5.995

Persistence of MRI hyperintensity of the globus pallidus in cirrhotic patients: A 2-year follow-up study

J. Kulisevsky, J. Pujol, J. Deus, C. Junqué, J. Balanzó, A. Avila, A. Capdevila

Department of Medicine

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Abstract

We investigated the long-term persistence and shortterm stability of globus pallidus (GP) hyperintensity on Trweighted MRI in 19 cirrhotic patients. After a mean interval of 25.8 months, the hyperintensity of the GP persisted in 17 patients. Hyperintensity disappeared in two patients with hepatocarcinoma, indicating that hyperintensity can revert to normal in circumstances other than liver transplants. Ten patients participated in a 6-month study with repeated evaluations of GP signal intensity, plasma ammonia levels, and selected neuropsychological tests. The GP signal was fairly stable during the follow-up, and the variables considered maintained significant relationships. GP hyperintensity appears as a stable indicator of the functional status of cirrhotic patients © 1995 American Academy of Neurology.

Original language	English
Pages (from-to)	995-997
Journal	Neurology
Volume	45
Issue number	5
DOIs	https://doi.org/10.1212/WNL.45.5.995
Publication status	Published - 1 Jan 1995

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title = "Persistence of MRI hyperintensity of the globus pallidus in cirrhotic patients: A 2-year follow-up study",

abstract = "We investigated the long-term persistence and shortterm stability of globus pallidus (GP) hyperintensity on Trweighted MRI in 19 cirrhotic patients. After a mean interval of 25.8 months, the hyperintensity of the GP persisted in 17 patients. Hyperintensity disappeared in two patients with hepatocarcinoma, indicating that hyperintensity can revert to normal in circumstances other than liver transplants. Ten patients participated in a 6-month study with repeated evaluations of GP signal intensity, plasma ammonia levels, and selected neuropsychological tests. The GP signal was fairly stable during the follow-up, and the variables considered maintained significant relationships. GP hyperintensity appears as a stable indicator of the functional status of cirrhotic patients {\textcopyright} 1995 American Academy of Neurology.",

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T1 - Persistence of MRI hyperintensity of the globus pallidus in cirrhotic patients: A 2-year follow-up study

AU - Kulisevsky, J.

AU - Pujol, J.

AU - Deus, J.

AU - Junqué, C.

AU - Balanzó, J.

AU - Avila, A.

AU - Capdevila, A.

PY - 1995/1/1

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N2 - We investigated the long-term persistence and shortterm stability of globus pallidus (GP) hyperintensity on Trweighted MRI in 19 cirrhotic patients. After a mean interval of 25.8 months, the hyperintensity of the GP persisted in 17 patients. Hyperintensity disappeared in two patients with hepatocarcinoma, indicating that hyperintensity can revert to normal in circumstances other than liver transplants. Ten patients participated in a 6-month study with repeated evaluations of GP signal intensity, plasma ammonia levels, and selected neuropsychological tests. The GP signal was fairly stable during the follow-up, and the variables considered maintained significant relationships. GP hyperintensity appears as a stable indicator of the functional status of cirrhotic patients © 1995 American Academy of Neurology.

AB - We investigated the long-term persistence and shortterm stability of globus pallidus (GP) hyperintensity on Trweighted MRI in 19 cirrhotic patients. After a mean interval of 25.8 months, the hyperintensity of the GP persisted in 17 patients. Hyperintensity disappeared in two patients with hepatocarcinoma, indicating that hyperintensity can revert to normal in circumstances other than liver transplants. Ten patients participated in a 6-month study with repeated evaluations of GP signal intensity, plasma ammonia levels, and selected neuropsychological tests. The GP signal was fairly stable during the follow-up, and the variables considered maintained significant relationships. GP hyperintensity appears as a stable indicator of the functional status of cirrhotic patients © 1995 American Academy of Neurology.

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DO - 10.1212/WNL.45.5.995

M3 - Article

VL - 45

SP - 995

EP - 997

JO - Neurology

JF - Neurology

SN - 0028-3878

IS - 5

ER -

Persistence of MRI hyperintensity of the globus pallidus in cirrhotic patients: A 2-year follow-up study

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