TY - JOUR
T1 - Persistence of Legionella in hospital water supplies and nosocomial Legionnaires' disease
AU - Garcia-Nuñez, Marian
AU - Sopena, Nieves
AU - Ragull, Sonia
AU - Pedro-Botet, Maria Luisa
AU - Morera, Josep
AU - Sabria, Miguel
PY - 2008/3/1
Y1 - 2008/3/1
N2 - The molecular epidemiology of clinical and environmental Legionella species isolates was studied in seven hospitals from 1989 to 2006. The number of environmental pulsed field gel electrophoresis (PFGE) patterns ranged from one to nine according to the hospital. Genomic PFGE pattern persistence was observed in 71% of the hospitals, even after 17 years in some hospitals, and the relationship between environmental and clinical isolates was established. The isolates associated with hospital-acquired Legionnaires' disease corresponded to the persistent environmental PFGE patterns of Legionella pneumophila in potable water supplies. © 2007 Federation of European Microbiological Societies.
AB - The molecular epidemiology of clinical and environmental Legionella species isolates was studied in seven hospitals from 1989 to 2006. The number of environmental pulsed field gel electrophoresis (PFGE) patterns ranged from one to nine according to the hospital. Genomic PFGE pattern persistence was observed in 71% of the hospitals, even after 17 years in some hospitals, and the relationship between environmental and clinical isolates was established. The isolates associated with hospital-acquired Legionnaires' disease corresponded to the persistent environmental PFGE patterns of Legionella pneumophila in potable water supplies. © 2007 Federation of European Microbiological Societies.
KW - Hospital-acquired Legionnaires' disease
KW - Legionella
KW - Persistence
KW - PFGE typing
U2 - 10.1111/j.1574-695X.2007.00362.x
DO - 10.1111/j.1574-695X.2007.00362.x
M3 - Article
SN - 0928-8244
VL - 52
SP - 202
EP - 206
JO - FEMS Immunology and Medical Microbiology
JF - FEMS Immunology and Medical Microbiology
IS - 2
ER -