Patient risk factors for developing a drug-related problem in a cardiology ward

Olatz Urbina, Olivia Ferrández, SòNia Luque, Sntiago Grau, Sergi Mojal, Rosa Pellicer, Marta Riu, Esther Salas, Josep Comin-Colet

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)


© 2015 Urbina et al. Background: Because of the high incidence of drug-related problems (DRPs) among hospitalized patients with cardiovascular diseases and their potential impact on morbidity and mortality, it is important to identify the most susceptible patients, who therefore require closer monitoring of drug therapy.Purpose: To identify the profile of patients at higher risk of developing at least one DRP during hospitalization in a cardiology ward.Method: We consecutively included all patients hospitalized in the cardiology ward of a teaching hospital in 2009. DRPs were identified through a computerized warning system designed by the pharmacy department and integrated into the electronic medical record.Results: A total of 964 admissions were included, and at least one DRP was detected in 29.8%. The variables associated with a higher risk of these events were polypharmacy (odds ratio [OR]=1.228; 95% confidence interval [CI]=1.153–1.308), female sex (OR=1.496; 95% CI=1.026–2.180), and first admission (OR=1.494; 95% CI=1.005–2.221).Conclusion: Monitoring patients through a computerized warning system allowed the detection of at least one DRP in one-third of the patients. Knowledge of the risk factors for developing these problems in patients admitted to hospital for cardiovascular problems helps in identifying the most susceptible patients.
Original languageEnglish
Pages (from-to)9-15
JournalTherapeutics and Clinical Risk Management
Publication statusPublished - 17 Dec 2014


  • Cardiovascular diseases
  • Clinical pharmacist
  • Computerized provider order entry
  • Drug therapy monitoring
  • Patient safety
  • Pharmacy warning system


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