Pathological lesions following an experimental intoxication with aflatoxin B 1 in broiler chickens

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    A follow-up of chickens dosed orally over 21 days with 0·2 and 3 μg of aflatoxin B 1 (afb 1 ) g -1 of bodyweight daily and their subsequent recovery 10 days after withdrawal of contaminated food was conducted. Vacuolation of liver cells during the initial days of the intoxication and cellular depletion in the follicle medulla of the bursa of Fabricius were the lesions which appeared first and persisted during the recovery phase in both groups of intoxicated animals. The intensity of these lesions and their persistence was related to the dose of aflatoxin ingested. A significant reduction in the bodyweight and absolute weights of liver, bursa of Fabricius spleen and thyroid was observed in the higher dose group. © 1992.
    Original languageEnglish
    Pages (from-to)275-279
    JournalResearch in Veterinary Science
    Issue number3
    Publication statusPublished - 1 Jan 1992


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