Pancreatic islet-cell antibodies in diabetic patients with other autoimmune diseases

R. Pujol-Borrell, C. Richart, S. Marti, J. M. Gomez

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Abstract

The presence of antibodies directed against pancreatic islet-cells was investigated in 18 insulin-dependent diabetic patients with autoimmune disease (Group 1), in 8 insulin-independent diabetic patients with autoimmune disease (Group 2), in 42 non-diabetic patients with thyroid antibodies (Group 3), in 18 patients with antibodies against gastric parietal cells (Group 4), and in 100 healthy subjects (controls). Islet-cell antibodies were found in 46% of group 1 patients and in only 1 patient of group 3 and 1 control. This would suggest the existence of a special form of autoimmune insulin-dependent diabetes, characterized by a high incidence of islet-cell antibodies and associated with other autoimmune diseases.
Original languageEnglish
Pages (from-to)2791-2793
JournalNouvelle Presse Medicale
Volume10
Issue number34
Publication statusPublished - 1 Jan 1981

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    Pujol-Borrell, R., Richart, C., Marti, S., & Gomez, J. M. (1981). Pancreatic islet-cell antibodies in diabetic patients with other autoimmune diseases. Nouvelle Presse Medicale, 10(34), 2791-2793.