The presence of antibodies directed against pancreatic islet-cells was investigated in 18 insulin-dependent diabetic patients with autoimmune disease (Group 1), in 8 insulin-independent diabetic patients with autoimmune disease (Group 2), in 42 non-diabetic patients with thyroid antibodies (Group 3), in 18 patients with antibodies against gastric parietal cells (Group 4), and in 100 healthy subjects (controls). Islet-cell antibodies were found in 46% of group 1 patients and in only 1 patient of group 3 and 1 control. This would suggest the existence of a special form of autoimmune insulin-dependent diabetes, characterized by a high incidence of islet-cell antibodies and associated with other autoimmune diseases.
|Journal||Nouvelle Presse Medicale|
|Publication status||Published - 1 Jan 1981|