Abstract
Pd(0)-Catalyzed allylation of six-membered ambident heterocycles bearing NH-CO, NH-CS and CH2-CO moieties obey the regioselectivity rules: C>O; N> S>N; NH-CO>NH-CS. Uracil and 5-methyluracil (thymine) do not show regioselectivity (N-1 = N-3) whereas 6-methyluracil is regioselectively allylated at N-3 (N-3>N-1). © 1993.
Original language | English |
---|---|
Pages (from-to) | 1457-1464 |
Journal | Tetrahedron |
Volume | 49 |
Issue number | 7 |
DOIs | |
Publication status | Published - 12 Feb 1993 |