TY - JOUR
T1 - P17-17. Newborn mice vaccination with rBCG:HIVA + MVA:HIVA enhances HIV-1-specific immune responses. Influence of age and immunization routes
AU - Saubi, N.
AU - Im, E.
AU - Fernandez-Lloris, R.
AU - Gil, O.
AU - Cardona, P.
AU - Gatell, J.
AU - Hanke, T.
AU - Joseph, J.
PY - 2009/10/22
Y1 - 2009/10/22
N2 - It has been demonstrated by several groups that the use of rBCG expressing HIV immunogens is a good priming vector for vaccinia based HIV vaccines, mainly in the prevention of mother-to-child HIV transmission. Our group has shown in Balb/C mice that rBCG:HIVA can both prime novel and boost preexisting HIV-1 specific cellular immune responses. In this study we have evaluated the HIV specific cellular immune responses induced after newborn and adult mice immunization using different routes with rBCG:HIVA prime and MVA:HIVA boost
AB - It has been demonstrated by several groups that the use of rBCG expressing HIV immunogens is a good priming vector for vaccinia based HIV vaccines, mainly in the prevention of mother-to-child HIV transmission. Our group has shown in Balb/C mice that rBCG:HIVA can both prime novel and boost preexisting HIV-1 specific cellular immune responses. In this study we have evaluated the HIV specific cellular immune responses induced after newborn and adult mice immunization using different routes with rBCG:HIVA prime and MVA:HIVA boost
UR - http://www.scopus.com/inward/record.url?scp=70449709268&partnerID=8YFLogxK
U2 - 10.1186/1742-4690-6-S3-P299
DO - 10.1186/1742-4690-6-S3-P299
M3 - Article
AN - SCOPUS:70449709268
SN - 1742-4690
VL - 6
SP - P299
JO - Retrovirology
JF - Retrovirology
IS - SUPPL. 3
M1 - 1742
ER -
