TY - JOUR
T1 - Overview of European pilot study of interferon beta-1b in primary progressive multiple sclerosis
AU - Montalban, X
PY - 2004/6
Y1 - 2004/6
N2 - This short monograph describes a trial of interferon beta-1b in patients with primary progressive multiple sclerosis (PPMS) or transitional MS. Designed as a randomized, placebo-controlled pilot, the trial randomly placed 73 eligible patients into two groups, placebo or interferon beta-1b 8 MIU given subcutaneously every other day for two years. Significant differences favouring interferon beta-1b in the MSFC score, T2 lesion volume and T1 lesion volume at 24 months were observed. Further study of interferon beta-1b therapy in PPMS patients is warranted.
AB - This short monograph describes a trial of interferon beta-1b in patients with primary progressive multiple sclerosis (PPMS) or transitional MS. Designed as a randomized, placebo-controlled pilot, the trial randomly placed 73 eligible patients into two groups, placebo or interferon beta-1b 8 MIU given subcutaneously every other day for two years. Significant differences favouring interferon beta-1b in the MSFC score, T2 lesion volume and T1 lesion volume at 24 months were observed. Further study of interferon beta-1b therapy in PPMS patients is warranted.
KW - Edss
KW - Mri
KW - Msfc
KW - Interferon beta-1b
KW - primary progressive MS
UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=uab_pure&SrcAuth=WosAPI&KeyUT=WOS:000221891300020&DestLinkType=FullRecord&DestApp=WOS
U2 - 10.1191/1352458504ms1033oa
DO - 10.1191/1352458504ms1033oa
M3 - Article
C2 - 15218812
SN - 1352-4585
VL - 10
SP - S62-S64
JO - Multiple Sclerosis Journal
JF - Multiple Sclerosis Journal
IS - 3 (suppl)
ER -