Outcome of intracytoplasmic sperm injection in relation to the meiotic pattern in patients with severe oligoasthenozoospermia

Objective: The aim of the study was to evaluate the intracytoplasmic sperm injection outcome in a selected group of patients with oligoasthenozoospermia in relation to the results obtained from their meiotic analysis. Design: Retrospective clinical study. Setting: An assisted reproduction service and a university department. Patient(s): One hundred thirty-seven men with oligoasthenozoospermia grouped in relation to their meiotic pattern. Intervention(s): Two hundred twenty-four intracytoplasmic sperm injection cycles from 137 men with oligoasthenozoospermia in whom diagnostic meiotic analyses had been performed. Main outcome measure(s): Fertilization, pregnancy, implantation, and abortion rates. Result(s): There were no significant statistical differences in fertilization, pregnancy, implantation, or abortion rates among the three groups studied. Conclusion(s): No statistically significant differences in fertilization, pregnancy, implantation, or abortion rates were found in patients with oligoasthenozoospermia in relation to the meiotic pattern. © 2003 by American Society for Reproductive Medicine.