Organizing pneumonia secondary to influenza infection: Two case reports and a literature review

Andrea Nuñez-Conde, Ester Marquez-Algaba, Vicenç Falcó, Benito Almirante, Joaquin Burgos

Research output: Contribution to journalArticleResearch

Abstract

© 2019 Elsevier España, S.L.U. and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica Background: Organizing pneumonia (OP)is a rare complication of influenza virus infection but scarce data are available. The recognition of this entity is important because require appropriate treatment. Methods: We report two cases and perform a systematic review on PubMed database. Only cases with histological confirmation of OP and influenza virus positive laboratory test were included. Results: We collected 16 patients. Median age was 52 year, 20% of patients were smokers and 43.8% had not any comorbidity. Influenza A virus infection was diagnosed in 75%. Clinical manifestation consisted on a respiratory deterioration with a median time of appearance of 14 days. Radiological pattern observed was ground-glass opacities with consolidations. Survival was observed in 12 patients (75%). All three patients who did not receive steroid treatment died. Conclusion: Physicians must be aware that patients with influenza infection with a torpid course could be developing OP and prompt corticoid therapy should be instaured.
Original languageEnglish
JournalEnfermedades Infecciosas y Microbiologia Clinica
DOIs
Publication statusPublished - 1 Jan 2019

Keywords

  • Bronchiolitis obliterans organizing pneumonia
  • Cryptogenic organizing pneumonia
  • Influenza virus
  • Secondary organizing pneumonia

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