This work evidences the suitability of applying a single twisted nematic liquid-crystal (TN-LC) device to obtain dynamic polarimeters with high accuracy and repeatability. Different Stokes polarimeter setups based on a TN-LC device are optimized, leading to the minimization of the noise propagated from intensity measurements to the Stokes vector calculations. To this aim, we revise the influence of working out of normal incidence and of performing a double pass of the light beam through the LC device. In addition, because transmissive TN-LC devices act as elliptical retarders, an extra study is performed. It analyzes the influence of projecting the light exiting from the TN-LC device over elliptical states of polarization. Finally, diverse optimized polarimeters are experimentally implemented and validated by measuring different states of partially and fully polarized light. The analysis is conducted both for monochromatic (He-Ne laser) and LED light sources, proving the potential of polarimeters based on a single TN-LC device. © 2011 Optical Society of America.