Oncosuppressive functions of tribbles pseudokinase 3

María Salazar; Mar Lorente; Alba Orea-Soufi; David Dávila; Tatiana Erazo; José Lizcano; Arkaitz Carracedo; Endre Kiss-Toth; Guillermo Velasco

doi:10.1042/BST20150124

Oncosuppressive functions of tribbles pseudokinase 3

María Salazar, Mar Lorente, Alba Orea-Soufi, David Dávila, Tatiana Erazo, José Lizcano, Arkaitz Carracedo, Endre Kiss-Toth, Guillermo Velasco

Research output: Contribution to journal › Article › Research › peer-review

19 Citations (Scopus)

Abstract

© 2015 Authors; published by Portland Press Limited. Tribbles pseudokinase 3 (TRIB3) belongs to the tribbles family of pseudokinases. In this article, we summarize several observation obtained by our laboratories supporting that TRIB3 plays a crucial role in the anti-cancer activity of cannabinoids (a novel family of potential anti-cancer agents derived from marijuana) and that TRIB3 genetic inactivation enhances cancer generation and progression.

Original language	English
Pages (from-to)	1122-1126
Journal	Biochemical Society Transactions
Volume	43
Issue number	5
DOIs	https://doi.org/10.1042/BST20150124
Publication status	Published - 1 Oct 2015

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Animal models of cancer
Autophagy
Cannabinoids
Endoplasmic reticulum (ER) stress
Tribbles pseudokinases

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10.1042/BST20150124

Cite this

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title = "Oncosuppressive functions of tribbles pseudokinase 3",

abstract = "{\textcopyright} 2015 Authors; published by Portland Press Limited. Tribbles pseudokinase 3 (TRIB3) belongs to the tribbles family of pseudokinases. In this article, we summarize several observation obtained by our laboratories supporting that TRIB3 plays a crucial role in the anti-cancer activity of cannabinoids (a novel family of potential anti-cancer agents derived from marijuana) and that TRIB3 genetic inactivation enhances cancer generation and progression.",

keywords = "Animal models of cancer, Autophagy, Cannabinoids, Endoplasmic reticulum (ER) stress, Tribbles pseudokinases",

author = "Mar{\'i}a Salazar and Mar Lorente and Alba Orea-Soufi and David D{\'a}vila and Tatiana Erazo and Jos{\'e} Lizcano and Arkaitz Carracedo and Endre Kiss-Toth and Guillermo Velasco",

year = "2015",

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doi = "10.1042/BST20150124",

language = "English",

volume = "43",

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TY - JOUR

T1 - Oncosuppressive functions of tribbles pseudokinase 3

AU - Salazar, María

AU - Lorente, Mar

AU - Orea-Soufi, Alba

AU - Dávila, David

AU - Erazo, Tatiana

AU - Lizcano, José

AU - Carracedo, Arkaitz

AU - Kiss-Toth, Endre

AU - Velasco, Guillermo

PY - 2015/10/1

Y1 - 2015/10/1

N2 - © 2015 Authors; published by Portland Press Limited. Tribbles pseudokinase 3 (TRIB3) belongs to the tribbles family of pseudokinases. In this article, we summarize several observation obtained by our laboratories supporting that TRIB3 plays a crucial role in the anti-cancer activity of cannabinoids (a novel family of potential anti-cancer agents derived from marijuana) and that TRIB3 genetic inactivation enhances cancer generation and progression.

AB - © 2015 Authors; published by Portland Press Limited. Tribbles pseudokinase 3 (TRIB3) belongs to the tribbles family of pseudokinases. In this article, we summarize several observation obtained by our laboratories supporting that TRIB3 plays a crucial role in the anti-cancer activity of cannabinoids (a novel family of potential anti-cancer agents derived from marijuana) and that TRIB3 genetic inactivation enhances cancer generation and progression.

KW - Animal models of cancer

KW - Autophagy

KW - Cannabinoids

KW - Endoplasmic reticulum (ER) stress

KW - Tribbles pseudokinases

UR - https://www.scopus.com/pages/publications/84947289710

U2 - 10.1042/BST20150124

DO - 10.1042/BST20150124

M3 - Article

SN - 0300-5127

VL - 43

SP - 1122

EP - 1126

JO - Biochemical Society Transactions

JF - Biochemical Society Transactions

IS - 5

ER -

Oncosuppressive functions of tribbles pseudokinase 3

Abstract

UN SDGs

Keywords

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